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colorimetric assay Introduction br Coronary revascularizatio
2018-10-22
Introduction Coronary revascularization Ischemic cardiomyopathy is caused by occlusive or obstructive coronary artery disease. Ischemic cardiomyopathy is now recognized as the most common cause of heart failure worldwide. It can be described in terms of three pathophysiological processes. (1) My
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An year old man presented with abrupt
2018-10-22
An 87-year-old man presented with abrupt, severe lower abdominal pain and a pulsatile right hip mass. The patient had had chronic obstructive pulmonary disease and benign prostate hyperplasia for more than 2 decades. The patient had frequent bursts of vigorous productive coughing associated with his
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Obesity in general is a predisposing factor
2018-10-22
Obesity in general is a predisposing factor of OA. There is a strong association between overweight and hip and knee OA. However, the association between overweight and ankle OA remains unclear. In Frey and Zamora\'s study regarding overweight and ankle OA, a total of 887 women and 535 men were incl
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In Taiwan a certification program on the
2018-10-22
In Taiwan, a certification program on the quality of cancer care in hospitals was initiated by the National Health Research Institutes in 2008. Establishing MDTs for cancer care is required for certification. The results of certification are available on a website for public access and influence nat
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Cecal volvulus is one of
2018-10-22
Cecal volvulus is one of the manifestations of intestinal malrotation and fixation abnormality. During embryogenesis, the mesentery of the right colon fuses with the lateral wall, resulting in cecal fixation. Cecal volvulus occurs in patients with a mobile cecum (nonfixation of the cecum and right c
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Discovery of longevity genes such as SirT gene
2018-10-22
Discovery of longevity genes such as SirT gene family has resulted in tremendous enthusiasm among many scientists. Numerous studies have shown that this gene family uses intermediate metabolites such as acetyl-CoA, ATP, and NAD+ or nucleosomes to modify and control the activity and expression of sta
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In the present study there is apparently no
2018-10-22
In the present study, there is apparently no compensatory mechanism in visceral organs in order to overcome STZ induced oxidative stress. Reduced activities of SOD and CAT in liver, kidney and heart have been observed during diabetes. SOD is vital defence enzyme which catalyses the dismutation of su
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br Acknowledgements This work is financially
2018-10-22
Acknowledgements This work is financially supported by the NSFC grant of 21475030, the S&T Research Project of Anhui Province15czz03109, the National 10000 Talents-Youth Top-notch Talent Program. Introduction Despite several advancement in medical sciences, cardiovascular disease (CVD) remain
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br Results br Discussion Controlling the chromosome
2018-10-22
Results Discussion Controlling the chromosome stability of hESCs and their derivatives remains a fundamental challenge in trials of hESC derivative-based cell therapy. In 2004, Andrew and co-workers reported that chromosomal instability during extensive hESC expansion was due to the alkaline p
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Mouse nhpESC chimeras were also prepared using the
2018-10-22
Mouse–nhpESC chimeras were also prepared using the mouse tetraploid complementation assay (Nagy, 2003). We electrofused mouse 2-cell embryos to produce 4N embryos and permitted these to develop to the expanded blastocyst stage before injecting them with GFP-expressing nhpESCs and performing embryo t
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Recently the properties of self
2018-10-22
Recently, the properties of self-renewal and pluripotency of human embryonic stem AZD6244 (hESCs) have paved the path for such studies (Koch et al., 2009; Yiping Yan et al., 2005). The in vitro differentiation of hESCs to neuronal cells serves as a model for study of early human neuronal developmen
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The increasing number of studies focusing
2018-10-22
The increasing number of studies focusing on regenerative medicine and stem cell transplantation is being accompanied by the development of techniques using many types of nanoparticles. The combination of nanotechnology with stem cell research may be able to address some challenges in this research
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The interaction between intact AM and limbal explants does n
2018-10-22
The interaction between intact AM and limbal explants does not only degrade the matrix of the AM but also activate intracellular signaling cascades triggered by matrix components. By use of selective pharmacological inhibitors, we investigated the downstream effectors critical for intact AM-induced
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Introduction The human epidermis is renewed monthly and dail
2018-10-22
Introduction The human AN-2728 Supplier is renewed monthly, and daily occurring wounds need timely repair. The processes involved in this regeneration and repair rely on epidermal stem cells, which generate colonies known as holoclones (Barrandon and Green, 1987; Pellegrini et al., 1999a; Rochat e
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Chondrogenic differentiation in our model is affected by der
2018-10-22
Chondrogenic differentiation in our model is affected by deregulation of LMNA, especially in PG-MSCs, as revealed by a lowered COL2/COL1 ratio and lower expression of COL2 and AGG as shown by real-time RT-PCR. While our findings do not completely agree with the results of the study by Scaffidi and M
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