• OCN is a marker of late

  2018-10-29

  

  OCN is a marker of late stage osteogenic differentiation and regulates matrix mineralization during bone formation. VitD3 had the greatest positive effect on this transcript while Dex had the greatest negative effect. This effect has previously been documented for VitD3 supplemented osteoblast cultu

• However when we started this work the data

  2018-10-29

  

  However, when we started this work, the data from the zebrafish and mouse studies had just been released, and a strategy to induce hematopoiesis in a stem cell population that could be obtained in very large numbers in the autologous setting seemed feasible, and with potentially huge implications in

• We demonstrated that the PI K AKT signaling pathway plays

  2018-10-29

  

  We demonstrated that the PI3K/AKT signaling pathway plays important roles in regulating hUCBSC differentiation and maintaining the pluripotency of hESCs (Yu et al., 2012). Furthermore, mTOR/p70S6K, a major downstream effector of PI3K/AKT signaling, was found to be phosphorylated, suggesting that HMG

• dna synthesis br Results br Discussion In the field of stem

  2018-10-29

  

  Results Discussion In the field of stem cell research, the demand for standardized media is rising, allowing for better reproducibility of results and thereby deepening our knowledge of the pathways regulating their maintenance and differentiation. Here, we set out to determine the minimum req

• Several studies have reported pivotal roles for

  2018-10-26

  

  Several studies have reported pivotal roles for some miRNAs in hBMSC-lineage commitment and fate determination that are mediated by their ability to modulate differentiation-regulating factors. For instance, miR-210, miR-206, miR-133, miR-2861, and miR-138 have been implicated in the regulation of o

• br Material and methods br Results br Discussion Pre transpl

  2018-10-26

  

  Material and methods Results Discussion Pre-transplant myeloablation has been consistently seen to be associated with an increase in the number of adipocytes in the bone marrow (Snyder, 1965; Naveiras et al., 2009; Cao et al., 2011). These marrow adipocytes were considered as passive space

• In this study we further show that expression of

  2018-10-26

  

  In this study, we further show that pop over to this website of SUV39H1 in HSC is controlled by the highly conserved miR-125 miRNA family. While previously shown to be important regulators of HSC self-renewal and differentiation potential (O\'Connell et al., 2010; Ooi et al., 2010), the contribution

• CD also known as CUB

  2018-10-26

  

  CD318, also known as CUB domain-containing protein 1, acts as a substrate for Src family kinases and is associated with the metastatic potential of cancer Anisomycin (Wortmann et al., 2009). In addition to cancer cells, CD318 has been reported to be present in several stem/progenitor populations suc

• These findings are particularly important when

  2018-10-26

  

  These findings are particularly important when you take into account the health selection process with respect to the incarcerated and noninstitutionalized populations for each group. Consider the values presented in Table 1 that describe the prevalence of each health problem for black and white men

• br Background and conceptual framework br

  2018-10-26

  

  Background and conceptual framework Methods Results The first three columns in Table 2 are from OLS models that regressed either physical (Panel A) or mental health (Panel B) on declaring bankruptcy. Model 1 assesses the bivariate relationship of bankruptcy and health, the next model added

• We agree with the position

  2018-10-26

  

  We agree with the position advocated within all of these methodological works that a coherent theoretical basis for intervention development, and use of evaluation to test key causal assumptions and build theory, are crucial. Viewing evaluation not simply as a stop/go test of effectiveness, but as a

• g-quadruplex The variable gender is the most studied

  2018-10-26

  

  The variable ‘gender’ is the most studied resource of the voice in the literature on radio. Its advertising effectiveness has been studied, although with contradictory results (Wolin, 2003). With our study, we attempt to contribute by determining whether the prevalence of male spokespersons detected

• The diagnosis of OSAS is one

  2018-10-26

  

  The diagnosis of OSAS is one of the key problems in this field. Although polysomnography is considered as the gold standard for the diagnosis of OSAS [1], this method is not yet widely available due, probably, to its high cost. Thus, some attempts have been made to develop self-report measures based

• br Method br Results br Discussion br Conflict of interest

  2018-10-26

  

  Method Results Discussion Conflict of interest Funding This work was supported by the APA Science Directorate. Introduction Obstructive sleep apnoea (OSA) is a common disease, with a prevalence of 3–5% symptomatic and 24–26% asymptomatic patients [1–3]. OSA is caused by episodic u

• br Medical literature robustly supports a close link between

  2018-10-26

  

  Medical literature robustly supports a close link between sleep disorders and psychiatric disorders. Recently, the co-occurrence of sleep dysfunctions and psychotic experiences (particularly insomnia with paranoia) has been reported, although the causal relationship is still unclear . Moreover, Re

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