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Several techniques have been set
2018-10-23
Several techniques have been set up to explore the therapeutic potential of miRs. miRs can be deactivated and silenced by anti-miR oligonucleotides (AMOs), “miR sponges”, and “miR masking” (McDermott et al., 2011). Conversely, other treatments simply restore their expression. This can be achieved th
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There are caveats with the above mentioned
2018-10-23
There are caveats with the above mentioned studies. First, there is no good method for accurately quantifying autophagy in vivo, and especially in human patients. This makes it difficult to be sure that drugs that increase autophagic flux in cultured Zalcitabine are also doing so in vivo. Second, a
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Diagnosis of ZIKV infection is performed
2018-10-23
Diagnosis of ZIKV infection is performed through detection of viral components (e.g., viral RNA, viral proteins, or virus isolation) and detection of host immune response (e.g., SC 144 against viral proteins). For viral component-based diagnosis, RT-PCR, immunoassay, and virus isolation detect ZIKV
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In a previous study we firstly uncovered
2018-10-23
In a previous study, we firstly uncovered the crucial role of NFAT5 in the development of autoimmune disease by demonstrating that NFAT5-deficient mice showed a marked lactacystin of antibody-induced arthritis (Yoon et al., 2011). Moreover, we have demonstrated that NFAT5 is highly expressed in the
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Regardless of the precise molecular mechanisms underlying th
2018-10-23
Regardless of the precise molecular mechanisms underlying the protrusion and metastasis impairing effect of RIOK1 depletion, our data already identify RIOK1 as a potential target for tumor therapy, as Marjon et al. (2016) have also recently suggested for MTAP deficient tumors. Indeed, RIO kinases ex
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br Value of the data br Data
2018-10-23
Value of the data Data, experimental design, materials and methods Sample preparation method In this investigation, concrete samples were fabricated using ordinary Portland cement, variable amounts fine and coarse aggregate and water (Table 1). Initially, required amount of cement was mixed
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AAK1 dual inhibitor manufacturer Value of the data br Data e
2018-10-23
Value of the data Data, experimental design, materials and methods Acknowledgments This work was financially supported by the grant sponsors: Shenzhen Municipal Committee of Science and Technology Innovation (Grant number: JC201105190969A) and the National Public Sector (AQSIQ) Special Funds
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Energy and exergy analysis results of
2018-10-23
Energy and exergy analysis results of a factory general process are seen in Table 8 in Ref. [1]. According to these results, the amount of factory total net energy transfer EnT=117,857.8 [kJ/pg] and total exergy loss ExT=75,579.8 [kJ/pg]. Factory total energy efficiency and exergy efficiency are fou
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br Experimental design materials and
2018-10-23
Experimental design, materials and methods Data The data include table and figures, which help analyze the phosphorylated peptides and DSP. The peptic peptides detected by LC FTICR MS after 5min rad001 of natural ovalbumin as control are listed in Supplementary Table 1. Compared with the cont
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br Experimental design materials and
2018-10-23
Experimental design, materials and methods The list of medulloblastoma cell lines was compiled from Cellosaurus, the controlled vocabulary of cell lines developed by the Swiss Institute of Bioinformatics [4], and the review by Xu et al. [5]. The relative percentage of citations for each cell line
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br Experimental design materials and methods The
2018-10-23
2. Experimental design, materials and methods The experiment was conducted at a rice field with long and short duration variety of BPT5204 (150 days) and IR64 (90–120 days), which normally yields 5.5 to 6.5t/ha-1 and 4.0 to 4.5t/ha-1 in 2013–2014 at rice field of Alapakkam: Latitude: 11.3600°N an
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Statistical analyses were done using the
2018-10-23
Statistical analyses were done using the SAS procedure PROC FREQ for Fisher׳s exact test, PROC MIXED for ANOVA followed by Dunnett׳s test, PROC GENMOD for GEE (SAS version 9.3, SAS Institute, Cary, NC, USA) and R version 3.2.5 scmamp package for Rom [5] adjusted p-value. The supplemental files to th
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The cavity finally disappears in S Table
2018-10-22
The cavity finally disappears in S4 (Table 2) fabricated at plunge depth of 0.25 mm owing to sufficient heat generation due to the adequate contact area of tool shoulder and workpiece. Distribution of reinforcement particles also becomes visibly uniform (see Fig. 4(d)). And SC layer depth becomes eq
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Las feministas abolicionistas armaron un repertorio de histo
2018-10-22
Las feministas abolicionistas armaron un repertorio de historias sobre mujeres inocentes leukotriene receptor antagonists quienes les fueron confiscados sus documentos, las obligaron a vender sus cuerpos y las engañaron y explotaron. Esas sobrecogedoras narraciones de victimización consolidaron una
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Las reflexiones que presento a continuaci
2018-10-22
Las reflexiones que presento W 54011 continuación son producto de una investigación etnográfica que realicé para obtener la maestría en Antropología Social de la BUAP. El artículo propone evidenciar la particularidad de la relación establecida entre cuidados y discapacidad con la intención de postul
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