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The neurogenic to gliogenic transition of NSPCs is
2018-10-24
The neurogenic-to-gliogenic transition of NSPCs is probably governed by a multi-layered system. The epigenetic status of astrocyte-specific (Takizawa et al., 2001) and neurogenic genes changes during development (Hirabayashi et al., 2009; Kishi et al., 2012; Pereira et al., 2010), critically determ
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Neuroanatomical studies indicate that DARPP neurons could be
2018-10-24
Neuroanatomical studies indicate that DARPP32+ neurons could be divided into two populations: one that constructs a direct pathway and another that constructs an indirect pathway. DARPP32+ neurons in the direct pathway express DRD1 and are located in the striosome. On the other hand, those in the in
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To address whether the bivalent state requires miRNAs or oth
2018-10-24
To address whether the bivalent state requires miRNAs or other Dicer-dependent functions, we reconstituted Dicer-deficient ESCs with miR-294, a member of the miR-290–295 miRNA family. ChIP-PCR showed that EZH2 binding was restored 48 hr later at the Gata3, Pax6, and Nr2f2 promoters (Figure 4B). Thus
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Actively dividing B cells aNSCs in our study were shown
2018-10-24
Actively dividing B1 anti fungal (aNSCs in our study) were shown to go through three rounds of divisions before differentiating into C cells (referred as TACs in our study) (Ponti et al., 2013). However, the mechanisms regulating their behavior both in vitro and in vivo are still not known. Our stu
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When we compared the in
2018-10-24
When we compared the in vivo MaSC activity using the gold standard mammary fat pad transplant assay, we found the CD24+ CD49fhi SCA-1neg cells had higher stem cell activity than the CD24+ CD49fhi SCA-1+ subset. Although the stem cell activity of the CD24+ CD49fhi SCA-1+ cells was limited (in vitro m
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br Introduction Mesenchymal stem stromal cells MSCs are
2018-10-24
Introduction Mesenchymal stem/stromal CB-5083 (MSCs) are an excellent biological source for bone regenerative therapies, tissue engineering, and treatment of post-menopausal osteoporosis (Murphy et al., 2013; Steinert et al., 2012). Ex vivo expansion of autologous bone marrow stromal cells and s
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The operator form of the expression
2018-10-24
The operator form of the expression for the interaction amplitude can be written in RPAE as [5]: This expression can also be written in the matrix form as where This expression can be also represented by diagrams, as shown in Fig. 1[5,6]. If the exchange terms are taken out of the sum of Exp
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We found little consistency in how
2018-10-24
We found little consistency in how adolescent neighbourhood social environments have been both conceptualised and operationalised. When operationalised the various concepts of adolescent neighbourhood measures were largely indistinct. Again, this is similar to findings from the previous review by Sa
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Table shows results from models partitioned
2018-10-24
Table 4 shows results from models partitioned by sex. In erk inhibitor to the pooled results, Model 2 of Table 4, our fully adjusted model, shows no statistically significant difference in the probability of being a current smoker among the first generation males in the sample by age at migration.
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One of the most important of these sciences the branch
2018-10-24
One of the most important of these sciences, the branch of biology and experimental psychology known as ethology, studies animal behaviour in both controlled and natural environments and examines how animals adapt to environmental change to improve their chances of survival. Human ethology studies a
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The GMM Difference estimator also
2018-10-23
The GMM Difference estimator – also known as the Arellano–Bond estimator – seeks to address the problem of endogeneity with the technique of instrumental variables. This methodology suggests the estimation in two steps. The problem encountered in GMM Difference is that in most cases the error term i
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In the sequel Nakane specifies the bank behavior assuming th
2018-10-23
In the sequel, Nakane (2001) specifies the bank behavior, assuming that a bank i is able to accumulate an amount D of deposits in real terms by committing to pay r as real interest, which is limited by a compulsory reserve rate μ. Besides the compulsory reserves, bank assets consist also by bank loa
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In addition to this introduction in the second section
2018-10-23
In addition to this introduction, in the second section is presented the methodology, the data, its corresponding sources, and the development accounting exercises results, according to the Hall and Jones (1999) methodology. In the third section the results with the human capital proxies that captur
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things Our voxel based morphometry analysis of the
2018-10-23
Our voxel based morphometry analysis of the S-NR group provided a more specific cluster of reduced volume within the left middle frontal gyrus — which improved the specificity of this step of the decision tree from 77% to 89%. At a whole things level no other GM regions were associated with this S-
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Patritumab is a fully human
2018-10-23
Patritumab is a fully human anti-HER3 monoclonal antibody that demonstrates antitumor activity when used alone or with anti-EGFR inhibitors in preclinical cancer models (Freeman et al., 2009). Patritumab inhibits HRG-mediated HER3 signaling by binding to the extracellular domain of HER3 (thus preven
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