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br Experimental design materials and methods br Acknowledgme
2018-10-25
Experimental design, materials and methods Acknowledgments This work was supported by a Grant from the Swedish Cancer Society. Specifications Table Value of the data Data, experimental design, materials and methods Using a quantitative shotgun proteomic approach (nLC–ESI–MS/MS) we ha
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Fig demonstrates cell damage induced by
2018-10-25
Fig. 2 demonstrates cell damage induced by ultra-sonication and evaluated by estimation of the total protein content of the cell suspensions. The data demonstrates that ultra-sonication of Sunitinib induces varying degrees of cell damage directly proportional to the duration of ultra-sonication rep
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Affective memory biases a key element
2018-10-25
Affective memory biases, a key element of the cognitive (Disner et al., 2011) and neuropsychological models of MDD (Roiser and Sahakian, 2013), are a common finding (Dalgleish and Werner-Seidler, 2014; Bradley and Mathews, 1988). Dalgleish and Werner-Seidler (2014) highlight the key components of th
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The hypothesis for the present study was that fluoxetine cou
2018-10-25
The hypothesis for the present study was that fluoxetine could influence cognitive processes that mature during juvenile telomerase inhibitor development. Specifically, sustained attention, recognition memory, and cognitive flexibility, cognitive abilities with a clear developmental trajectory in p
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br Discussion We reported the success and
2018-10-25
Discussion We reported the success and satisfactory results of SIH in a series of patients with basal cell carcinoma of the face after excision. In the current era of elegant and elaborate reconstructive techniques, SIH is often underutilized. However, under certain circumstances, SIH can offer f
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br Conclusions br Acknowledgements The authors
2018-10-25
Conclusions Acknowledgements The authors wish to express their sincere thanks to M/s Mailam India Ltd, Pondicherry, India for providing the funds to carry out this hcv protease inhibitors research work through Mailam India Research (MIR) Fellowship, M/s Salzgitter Mannesmann Stainless Tubes It
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The chips in machining experience plastic deformation
2018-10-25
The chips in machining experience plastic deformation and shear fracture along a plane that blasticidin is inclined at an angle α, which is known as shear angle and estimated as [22,29,30]where γ is the mean friction angle along tool–chip interface, ; and β is the rake angle that depicts the inclina
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Proponemos el t rmino Capitalismo Gore para hacer
2018-10-25
Proponemos el término Capitalismo Gore, para hacer referencia a la reinterpretación dada a la economía hegemónica y global en los espacios (geográficamente) fronterizos. En nuestro caso pondremos como ejemplo, de dicho fenómeno, a la ciudad de Tijuana, frontera ubicada entre México y los Estados Uni
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br Biochip Microarray provides rapid accurate
2018-10-25
Biochip/Microarray provides rapid, accurate, high throughput measurements for proteins and nucleic acids, which is a promising technology in many biomedical fields Biochips are essentially miniaturized laboratories. Microarray is the critical component of a biochip platform. Microarrays consists
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br Cardiac niches and the Notch receptor system
2018-10-24
Cardiac niches and the Notch receptor system The Notch pathway is an evolutionary conserved intercellular and intracellular mechanism that controls stem cell fate (Bray, 2006). The Notch gene family encodes transmembrane receptors that are activated by ligand binding and proteolytic cleavage, res
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An important question that remains an area of ongoing
2018-10-24
An important question that remains an area of ongoing work is to determine whether the sustained presence of Tregs after hNPC rejection continues to dampen neuroinflammation long term. We believe this is possible because hNPCs had already disappeared from the spinal cord at the time we detected incr
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As a potential platform to model HD cellular pathogenesis
2018-10-24
As a potential platform to model HD cellular pathogenesis, an important goal of this study was to assess whether our cellular model recapitulates disease-associated pathologic events. We found that an increase of intranuclear inclusions and the accumulation of oligomeric, soluble, and insoluble mHTT
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Although the disease specific phenotype
2018-10-24
Although the disease specific phenotype identified in this study will be invaluable for demonstrating the efficacy of gene based therapeutics, two major questions remain: 1) why do some patients with TRNT1 variants develop the severe syndromic disease SIFD while others (i.e. the three presented in t
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br Materials and Methods br Results
2018-10-24
Materials and Methods Results Discussion The importance of bone marrow microenvironment in leukemogenesis becomes more evident each day. Kim and colleagues described the ability of leukemic stem neuropeptides to reset the communication between hematopoietic stem cells and the bone marrow m
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WNT signaling is well recognized for its role
2018-10-24
WNT signaling is well recognized for its role in regulating stem and progenitor orexin receptor antagonist in diverse systems (Nusse et al., 2008). Elevated levels of β-catenin, indicative of aberrant WNT signaling, are reported in more than 50% of human breast carcinomas, correlate with poor progno
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