• Typical examples of CO utilization and reduction technologie

  2020-02-25

  

  Typical examples of CO2 utilization and reduction technologies are catalytic reduction of CO2 to C1 compounds such as CO, formic acid, methanol and so on [[3], [4], [5], [6], [7], [8], [9], [10]], and catalytic organic synthesis using CO2 as a feedstock [[11], [12], [13], [14], [15], [16], [17], [18

• selinexor Here we were able to show for the first time

  2020-02-25

  

  Here, we were able to show for the first time that stimulation of VSMCs with two different growth factors resulted in a dramatic decrease in gp130mRNA expression occurring four to six hours after stimulation with Ang II and PDGF-BB. The mRNA level remained extremely low within 12 hours after stimula

• Since its inception ADEPT approach

  2020-02-25

  

  Since its inception, ADEPT approach has been widely reported by many groups using a variety of enzymes and prodrugs (see reviews) [12], [14]. Both mammalian and non-mammalian enzymes have been utilised. Of the mammalian variety, human β-glucuronidase in combination with many prodrugs [17], [18] and

• The inhibition of CYP activity

  2020-02-25

  

  The inhibition of CYP11β activity by NOR was 11- and 2.5-fold higher than those reported for the antifungal agents ketoconazole (IC50: 4.4μM) and clotrimozole (IC50: 1.0μM) (Fernandes and Porte, 2013). Furthermore, NOR was able to inhibit P450 aromatase activity in carp ovaries, although at a rather

• Our study shows that deletion

  2020-02-25

  

  Our study shows that PLX4720 synthesis of Dpf2 in mouse ESCs decreased their self-renewal ability and dramatically impaired their differentiation into mesoderm and endoderm while promoting neural ectoderm differentiation. The differentiation defect to meso-endoderm could be rescued by restoring Tbx

• Fujimoto et al pointed out

  2020-02-25

  

  Fujimoto et al. pointed out that RPN2 knockout alleviated the resistance of GC DOI hydrochloride sale (MKN74 and KATO III) to docetaxel and DDP [23]. Yuan et al. demonstrated that the depletion of RPN2 resulted in the reduction in resistance of GC cells to drugs such as irinotecan, docetaxel, doxor

• There are conflicting studies on ET axis and

  2020-02-25

  

  There are conflicting studies on ET axis and its relationship with clinicopathologic parameters in various cancers. Endothelin axis expression in the tissue and in blood has been associated with advanced cancer characteristics in colorectal, breast, and prostate cancer, while showing no linkage to c

• Both receptors belong to the

  2020-02-25

  

  Both receptors belong to the large family of G protein-coupled receptors (GPCRs) [4,5], which often appeared as monomers, dimers and higher order aggregates [6,7]. There is evidence that these receptor-complexes can modulate the functionality and the pharmacology of the receptors [8,9] by sequesteri

• The activity of cysteine endopeptidases involved in the germ

  2020-02-25

  

  The activity of cysteine endopeptidases involved in the germination of caryopses is generally regulated at two levels: the hormonal induction of synthesis by gibberellins (Drzymała et al., 2008) and a putative regulation of activity by phytocystatines (Kiyosaki et al., 2007, Martinez et al., 2009),

• Immunofluorescence assays were performed to localize the

  2020-02-25

  

  Immunofluorescence assays were performed to localize the enzyme during growth and differentiation to further characterize Giardia E1. As stated before, the assays showed that the moclobemide generated recognized specific E1 forms (E1-114, E1-90 and E1-67 with anti-gNTE1; and E1-47 with anti-gE1CT);

• The E enzyme is the

  2020-02-25

  

  The E1 enzyme is the apex for downstream enzymatic cascades and signaling pathways mediated by Ub and Ub-like proteins (Ubls) (Pickart, 2001). Studying characteristics of E1 and its catalytic functions may throw light to the role of ubiquitination in cell development. All known eukaryotic E1 are mon

• br Restenosis after angioplasty remains a remarkable

  2020-02-25

  

  Restenosis after angioplasty remains a remarkable challenge, although drug-eluting stents have reduced the incidence of restenosis considerably . Vascular smooth muscle Actinomycin D australia (VSMCs) play a pivotal role in the development of intimal thickening and restenosis. VSMCs proliferate a

• Soybean Glycine max is an

  2020-02-25

  

  Soybean (Glycine max) is an important oilseed and can be a useful source of epoxy fatty acids (EFAs). This UFA contains an oxygen bridge across adjacent carbon atoms at single or multiple positions in the acyl chain, making them highly reactive and prone to cross-linking, and thus valuable industria

• These studies suggested that PV PVH might

  2020-02-24

  

  These studies suggested that PV/PVH might promote bone formation activities and/or inhibit bone resorption activities probably due to its anti-inflammation activity; however, the underlying mechanism remained unknown. Furthermore, it is unclear if PVH shows better activity than that of PV; this is i

• We also observed reduced insulinotropic effects

  2020-02-24

  

  We also observed reduced insulinotropic effects after intravenous administration of both GLP-1 and GIP with atropine, whereas no inhibition was observed by atropine of the direct effects of GLP-1 and GIP action on beta-cells in the islet experiments. This suggests that the reduction in circulating i

14920 records 802/995 page Previous Next First page 上5页 801802803804805 下5页 Last page